A elevated level of plasma reistin and microinflammation in maintenance hemodialysis patient
- VernacularTitle:维持性血透患者高抵抗素血症及其意义探讨
- Author:
Ling ZHONG
- Publication Type:Journal Article
- Keywords:
Maintenance hemodialysis;
Resistin;
Microinflammation
- From:
Journal of Chongqing Medical University
2007;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate plasma resistin lever in maintenance hemodialysis(MHD)patients and explore its relationship with micruinflammation. Methods:73 patients with MHD and 20 heahhy volunteers were involved in this study. Plasma concentrations of IL-6, TNF-?, resistin were measured by enzyme linked immunoassay(ELISA). The serum levels of high sensitivity C-reactive protein (CRP), triglyceride, cholesterol, albumin, glucose and insulin were also detected. The homeostasis model assessment index(HOMA-R) was calculated as an estimate of insulin resistance from the fasting glucose and insulin. Results:The plasma lever of resistin in MHD was significantly increased compared with healthy controls(40.15?22.46 vs 11.78?6.29 ug/L, P
