Expression of HOXa-10 gene in endometrium mice during early pregnancy
- VernacularTitle:HOXa-10在早孕小鼠子宫内膜中的表达
- Author:
Yongcun JIA
- Publication Type:Journal Article
- Keywords:
HOXa-10;
Blastocyst implantation;
Heal-time fluorescence quantitative PCR;
Immunohistochemical
- From:
Journal of Chongqing Medical University
2007;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of HOXa-10 gene in the mouse uterus during embryo implantation. Method: real-time fluorescence quantitative PCR (FQ-PCR) and immunohistochemistry were used to detect the HOXa-10 gene and protein of the mouse of un-pregnant pregnant d1,d2,d3,d4,d5 and d7. Result:The HOXa-10 mRNA/?-actin mRNA expression in pregnant group is higher than that of non-pregnant grnup, and the results showed gradual hoist trend as days past, the HOXa-10 mRNA expression reached the maximum at pregnant d4. Immunohistochemical analysis showed the same results as FQ-PCR. Conclusion:HOXa-10 is persistently expressed in mouse endometrium during the early pregnancy and maybe participates in the regulation process of mouse blastodyst implantation.
