Study on the Effective Constituents with Estrogenic Action in Fructus Psoraleae
- VernacularTitle:补骨脂雌激素样作用的有效成分研究
- Author:
Qingyao SHOU
;
Rongping YANG
;
Binhao WANG
;
Jianyi LIU
;
Jiahong XU
- Publication Type:Journal Article
- Keywords:
Fructus psoraleae;
Estrogenic action;
Effective constituents
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To screen out the effective constituents with estrogenic action in Fructus psoraleae. Methods Fructus psoraleae was separated by using systemic solvent distillation method, and the effective fraction was screened out by the experiment of increasing the uterine weight in mice. Then the petroleum fraction was separated by sil; ca gel chromatrography and the effective constituent was screened by the experiment of increasing the uterine weight in mice. Results High-dose(5g/kg) of the petroleum fraction showed obvious estrogenic action (P
