Effects of MPD on Heart Hemodynamics in Normal Anesthetic Dogs
- VernacularTitle:薯蓣皂苷元对正常麻醉犬心脏血流动力学的影响
- Author:
Keyong NING
;
Huili GAO
;
Yikui LI
;
Lianda LI
- Publication Type:Journal Article
- Keywords:
Methy protodioscin;
Hemodynamics;
Peripheral vascular resistance
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pharmacological effects of MPD on heart hemodynamics and myocardial oxygen consumption in dogs, and to study its mechanism. Methods The changes of parameters such as blood pressure (BP), coronary blood flow, myocardial oxygen consumption and heart rates were observed in normal anesthetic dogs. Results Compared to those in the normal group, MPD can obviously lower the BP and peripheral vascular resistance, dilate the coronary and peripheral artery, increase the coronary blood flow and improve the left ventricle function and myocardium oxygen consumption rate. Conclusion MPD can improve the heart hemodynamics and regulate myocardium oxygen consumption.
