The expression and significance of PPAR ? in chronic hepatitis B tissues
- VernacularTitle:PPAR ?在慢性乙型病毒型肝炎患者肝组织中的表达及意义
- Author:
Yi LI
- Publication Type:Journal Article
- Keywords:
PPAR?;
Chronic hepatitis b;
Hepatic tissue
- From:
Journal of Chongqing Medical University
2007;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To detect the relation of peroxisome proliferators actived receptor ?(PPAR?)in the hepatic tissue of chronic hepatitis B and explore its significance.Methods:The protein and mRNA expression of PPAR? was detected by means of immunohistochemistry and semi-quantitative RT-PCR in cases of hepatic fibrosis staging S0-S4 of chronic hepatitis B and cases of hepatic hemangioma.The average of A values was obtained by image analysis.Results:There was not obvious correlation between PPAR? level and the hepatic activity index.Positive staining of PPAR? was observed in all of the human liver tissues.The expression of PPAR?in tissues of staging S0 and normal liver was stronger than that in tissues of staging S3 and staging S4(P
