Quality standard of Breviscapine Orally Disintegrating Tablets
- VernacularTitle:灯盏花素口腔崩解片质量标准的研究
- Author:
Yisheng ZHOU
;
Dongyan ZHAI
;
Qionghui DUAN
;
Meisong QIN
;
Yinku XIAN
- Publication Type:Journal Article
- Keywords:
scutellarin;
orally disintegrating tablets;
quality evaluation
- From:
Chinese Traditional Patent Medicine
1992;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To establish quality control method for Breviscapine(Orally) Disintegrating Tablets. METHODS: Its main ingredient scutellarin was identified by TLC, the scutellarin in the tablets was determined by HPLC.And the disintegration, dissolution rate and tablet weights were determined. RESULTS: Breviscapine(Orally) Disintegrating Tablets could be disintegrated in 30 seconds,and the tablet weight was fit for the criterion.And the dissolution rate was more quick than the original Breviscapine tablets in the market.A good linearity was obtained within the range of 0.081 6 ?g-0.408 0 ?g with the correlation coefficient(0.999 9.) The recovery was(99.67%) and RSD was 0.47%. CONCLUSION: The method for identifying and determing Breviscapine Orally Disintegrating Tablets is simple,reproducible and practical.
