Effect of Immunoregulatory Activity of Eucommia Ulmoides Oliv Polysaccharides on Immunodepressive Mice
- VernacularTitle:杜仲总多糖对环磷酰胺致免疫低下小鼠的影响
- Author:
Xiaoming XIN
;
Hao WANG
;
Lei FENG
- Publication Type:Journal Article
- Keywords:
eucommia ulmoides oliv polysaccharides;
cyclophasphamide;
immunoregulotory activity;
mice
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the immunoregulatory activity of eucommia ulmoides oliv polysaccharides (EOP) on immunodepressive mice. Method The immunodepressive mice model was established with cyclophosphamide (CY) treated. EOP was given with different doses, and mouse weight, thymus index, spleen index, abdominal cavity macrophage engulfing rates, engulfing index were measured. Result 300 grams Eucommia ulmoides Oliv crude drugs after withdraw separate gained 9.3 grams polysaccharides. After CY injection, the mouse weight, chest gland index, abdominal cavity macrophage swallowing rate, phagocytic count reduced. EOP could resist the mouse body weight drop induced by CY, elevate the thymus index of immunity low mouse, obviously increase mouse abdominal cavity macrophage engulfing rates and engulfing index (P
