Influence of Mahong Decoction on Serum VEGF and b-FGF of Rat Model of Bronchus Asthma Airway Remolding
- VernacularTitle:麻红止哮合剂对哮喘气道重塑大鼠血管内皮生长因子与碱性成纤维细胞生长因子浓度的影响
- Author:
Yanping ZHANG
;
Fangnan CUI
;
Qing MIAO
- Publication Type:Journal Article
- Keywords:
bronchus asthma;
airway remolding;
VEGF;
b-FGF;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Mahong decoction on serum VEGF and b-FGF of rat model bronchus asthma airway remolding. Method Forty SD rats randomly divided into four groups: blank group, asthma group, hormone group, Chinese medicine group. The asthmatic model was established by sensitization and challenge with ovalbumin, and the rats in the hormone group and Chinese medicine group conferred hormone and Chinese medicine before the challenge. ELISA was used to measure the level of serum VEGF and b-FGF. Results The serum VEGF and b-FGF in asthma group was higher than in other groups (P0.05). Conclusion Mahong decoction may control the level of serum VEGF and b-FGF of rat model of bronchus asthma airway remolding, which has the similar result with hormone.
