Influence factors on preparation of citrus volatile oil microcapsules by spray drying technique
- VernacularTitle:喷雾干燥法制备陈皮挥发油微囊的影响因素考察
- Author:
Yi FENG
;
Ying ZHANG
;
Yin YANG
;
Desheng XU
- Publication Type:Journal Article
- Keywords:
citrus volatile oil;
spray drying;
microcapsule;
uniform design
- From:
Chinese Traditional and Herbal Drugs
1994;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence factors on preparation of citrus volatile oil microcapsules by spray drying technique.Methods The citrus volatile oil microcapsules were prepared by spray drying technique with arabic gum as coating material.The temperature of aeration,injection speed,spray rate of flow,and exhausting volume were observed by single factor and the technical parameters were optimized by uniform design.Results The optimum condition including ratio of drug to coating material(0.9),plasticizer to coationg material(0.15),the temperature of aeration(145 ℃),injection speed(18 mL/min);and spray rate of flow(40 L/h).The microcapsules prepared by optimum conditions were smooth and possessed average encapsulation efficency in 84.50%,average drug loading in 28.32%.Conclusion The optimum conditions are chosen reasonably,which can increase the stability of citrus volatile oil microcapsules significantly.
