Protective Effects of Ethanol-extract of Halenia elliptica on Chemical Hepatic Injury in Mice
- VernacularTitle:椭叶花锚醇提物对化学性肝损伤小鼠的保护作用
- Author:
Lan JIN
;
Yuebin GE
;
Guihua LUO
;
Li DING
;
Zhi CHEN
- Publication Type:Journal Article
- Keywords:
Ethanol-extract of Halenia elliptica D. Don;
Hepatic injury;
Mice;
ALT;
AST;
Liver glycogen
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protective effects of ethanol-extract of Halenia elliptica D. Don on chemical hepatic injury in mice. Methods Mouse models of chemical hepatic injury were induced by intraperitoneal injection of 0.12 %CCL4. Extract of Halenia elliptica D. Don by alcohol was administered,and serum ALT,AST activities and liver glycogen level were measured in mice. Results Compared with the models,the enzyme activities of ALT and AST were significantly reduced and the content of liver glycogen was significantly increased in the ethanol-ex tract of Halenia elliptica groups. Conclusion It is indicated that ethanol-extract of Halenia elliptica D. Don has an effect in protecting the liver.
