Curative Mechanism of Jieyuan Capsule on Rats Renal Failure Induced by 5/6 Nephrectomy
- VernacularTitle:洁源胶囊对大鼠肾衰模型的防治作用机理研究
- Author:
Xiaolin ZHAO
;
Ping CHANG
;
Yi ZHOU
;
Hongzhu DENG
- Publication Type:Journal Article
- Keywords:
Jieyuan Capsule;
Chronic renal failure;
5/6 nephrectomy;
Blood urea nitrogen;
Serum creatinine
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the curative mechanism of Jieyuan (JY) Capsule on rats renal failure induced by 5/ 6 nephrectomy. Methods Chronic renal failure (CRF) rat models induced by 5/6 nephrectomy were administered with JY Capsule. The serum levels of blood urea nitrogen (BUN) and serum creatinine (Scr),hematological and biochemical indexes,and renal histological features were observed. Results JY Capsule reduced levels of BUN and Scr,ameliorated the electrolyte,increased the number of red blood cell and hemoglobin content,and alleviated pathological changes of the kidney tissue. Conclusion JY Capsule can relieve the rat CRF symptoms and postpone the progress of CRF.
