Investigation on anti-microorganism and cytotoxic properties of alkaloids from some species of Crinum in Vietnam
- Author:
Phan Tong Son
- Publication Type:Journal Article
- Keywords:
alkaloid* anti-microorganism, cytotoxic property
- MeSH:
Alkaloids;
Cytotoxins;
Crinum;
Anti-Bacterial Agents
- From:Pharmaceutical Journal
2003;234(4):18-21
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Investigation on anti-microorganism and cytotoxic properties of alkaloids from Crinum latigolium L. and Crinu asiaticum L. (Amaryllidaceae) growing in Vietnam and seven pure alkaloids from these plants. The total alkaloids from C.latifolium L. and C. asiaticum L/ showed a strong effect against Sarcina lutea while pratorinine was found to be active against Staphylococcus aureus. Among the evaluated alkaloids, lycorine showed a very strong cytotoxic activity on Hep-G2, RD and Fi and 1-O-acetyl – lycorine exhibited a moderate activity on Hep-G2. The remaining alkaloids were found not to be cytotoxic in all tested cell lines.
