Separation and purification of total alkaloid from Rhizoma Coptidis by macroreticular adsorbent resin
- VernacularTitle:大孔吸附树脂分离纯化黄连总生物碱的工艺研究
- Author:
Xiaohong XU
;
Tiejun ZHANG
;
Maoliang LIAO
;
Keyue LIU
;
Wenfang WANG
;
Yanji WU
- Publication Type:Journal Article
- Keywords:
Rhizoma Coptidis;
total alkaloids;
AB-8 resin;
separation and purification
- From:
Chinese Traditional and Herbal Drugs
1994;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the technology for purification of total alkaloids from Rhizoma Coptidis by maeroreticular adsorbent resin.Methods LD605,D101,DA201,NKA-9,and AB-8 types of macroreticular adsorbent resins werre used to separate and purify the total alkaloid from Rhizoma Coptidis.The yields and purities of the products were compared as indexes.Results AB-8 Type macroreticular adsorbent resin had optimum adsorption and elution parameters with its dynamic saturated adsorption ratio up to 1.23 mg/g.After eluted with 2 BV of distilled water and 2 BV 40% ethanol,the yields of total alkaloid was 85%,and content was 80%.Conclusion The AB-8 type macroreticular resin showsa better comprehensive adsorption property and can be used to separate and purify the total alkaloids from Rhizoma Coptidis.
