Effects of puerarin on related cytokines in myocardial hypertrophy in rats
- VernacularTitle:葛根素对大鼠心肌肥厚的相关细胞因子的影响
- Author:
Ling ZHANG
;
Hongxin WANG
;
Zhimin QI
;
Yuan SUN
- Publication Type:Journal Article
- Keywords:
puerarin;
isoproterenol;
endothelin;
nitrogen monoxide;
angiotensin Ⅱ;
myocardial hypertrophy;
rat
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effect of puerarin (Pue) on related cytokines in myocardial hypertrophy induced by isoproterenol (Iso) in rats. METHODS: 40 SD rats were randomly divided into 4 treatments groups: control group, Iso group, Iso+Pue group (Pue group) and Iso+Captoril (Cap) group (Cap group), with 10 rats each group. Ratio of ventricle weight to heart weight, cardiomyocyte diameter, plasma and myocardial tissue NO, ET and Ang Ⅱ levels were measured. RESULTS: Compared with the control group, Iso did induce significant changes in cardiac hypertrophy (P
