The evaluation of CT-guided interstitial ~(125)I seeds implantation in combined chemotherapy for non-small cell lung cancer
- VernacularTitle:CT引导下~(125)I放射性粒子组织间植入联合化疗治疗非小细胞肺癌的评价
- Author:
Dougui ZHAO
;
Sujun YANG
;
Zhiyuan GUO
;
Zhiguo FU
;
Lvping FU
;
Xinping NIE
- Publication Type:Journal Article
- Keywords:
CT-guided;
Lung cancer;
~(125)I seeds implantation;
Chemotherapy
- From:
Journal of Interventional Radiology
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical value of CT-guided percutaneous embedding of 125I seeds in combined chemotherapy with TP regime for non-small cell lung cancer(NSCLC). Methods Thirty two patients with NSCLC received CT-guided percutancous embedding of 125I particles, TP chemotherapy plan (paclitaxcl 135 mg/m2 /d1, cisplatin 75 mg/m2/d2 ～ 4 ) for four cycles after operation. The follow-up CT for observing therapeutic effects at 1, 3, 6, 12 month after 125I seeds implantation was undertaken. Results All cases were controlled effectively after one month revealed by CT follow up. The efficiency of tumor curing at 3, 6, 12 month were 87.5%, 90.63%, 92.31% respectively. None of the patients showed radiation injury and particle migration, and all of them had only slight side effects. Conclusion CT-guided percutaneous embedding of 125I seeds in combination with chemotherapy for non-small cell lung cancer is an effective and safe method, possessing valuable utilization clinically.
