Effect of Treatment of Warming Yang and Supplementing Heart Qi on Serum CRP and IL-6 of Rats with Atherosclerosis
- VernacularTitle:温阳益心法对动脉粥样硬化大鼠血清C反应蛋白和白细胞介素-6水平的影响
- Author:
Danli TANG
;
Hongxin CAO
;
Huamin ZHANG
- Publication Type:Journal Article
- Keywords:
the treatment of warming yang and supplementing heart qi;
atherosclerosis;
CRP;
IL-6;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the precautionary mechanism of atherosclerosis by observing the effect of the treatment of warming yang and supplementing heart qi on inflammaory factors levels in atherosclerosis rat serum. Method 72 rats were divided into 6 groups randomly:normal group,model group,simvastatin group and three groups with different dose of Chinese herbal medicine. An animal model of AS was established by injecting vitamine E in high fat-fed rats. When the model was established successfully,corresponding medicine were supplied for 6 weeks and then the contents of CRP and IL-6 in rat serum were measured. Results The levels of CRP and IL-6 were significantly higher in model groups than the normal group (P