Experimental Study of Jiangzhi Yigan Chongji on PPAR? and Trx mRNA of Liver Tissue of Nonalcoholic Fatty Liver Model Rats
- VernacularTitle:降脂益肝冲剂对非酒精性脂肪肝大鼠肝组织PPAR?及Trx mRNA表达的影响
- Author:
Heping ZHAO
;
Xiaoyan DUAN
;
Gehong ZHANG
- Publication Type:Journal Article
- Keywords:
Jiangzhi Yigan Chongji;
nonalcoholic fatty liver;
rat;
PPAR? mRNA;
Trx mRNA
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Jiangzhi Yigan Chongji (JYC) on the nonalcoholic fatty liver tissue PPAR? and Trx mRNA expression,and explore the mechanism of treating fatty liver. Methods The model was made by feeding high-fat diet and the rats were divide into 3 groups:normal group,model group and treated group. Result Expression of liver tissue PPAR? and Trx mRNA in the model group were both decreased. JYC can increase their expression of liver tissue of model rats. Conclusion It is likely to be one of the important mechanisms for JYC in treating nonalcoholic fatty liver.
