Effect of Huazhuo Jiedu Huoxue Recipe on plasma orphanin FQ and prostaglandins in the patients of endometriosis with pain
- VernacularTitle:化浊解毒活血方对子宫内膜异位症患者血浆孤啡肽及前列腺素的影响
- Author:
Shuhong SHI
;
Diangui LI
;
Xianxin MENG
- Publication Type:Journal Article
- Keywords:
endometriosis;
pain;
orphanin FQ;
prostaglandins;
Huazhuo Jiedu Huoxue Recipe
- From:
Chinese Traditional Patent Medicine
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To evaluate the effect of Huazhuo Jiedu Huoxue Recipe(Herba Agastaches,Herba Eupatorii,Rhizoma Pinelliae,Pericarpium Citri reticulatae,Poria,etc.) on plasma orphanin FQ(OFQ) and prostaglandins in the patients of endometriosis(EM) with pain.METHODS:The concentrations of plasma OFQ and prostaglandins were measured by radioimmunoassay before and after the treatment on the patients of EM with pain.29 patients of EM with severe pain(severe group),31 patients with slight pain(slight group) and 25 patients without pain(control group) were studied.RESULTS:The levels of OFQ、 PGF_(2a)、 PGE_2、 6-keto-PGF_(1a) and TXB_2 in plasma were significantly higher in patients of EM with pain than that of patients without pain(P
