The application of five serum markers in therapeutic effectiveness evaluation with breast cancer
- VernacularTitle:五种血清标志物在乳腺癌疗效评价中的应用
- Author:
Han GAO
- Publication Type:Journal Article
- Keywords:
Markers;
Breast cancer
- From:
Journal of Chongqing Medical University
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To approach the change of five serum markers such as CA15-3、CA125、CEA、CYFRA21-1 and TPS with breast cancer between pre-and post-neoadjuvant chemotherapy,to screen the better treatment effectiveness evaluation markers.Methods:The serum markers such as CA15-3、CA125、CEA、CYFRA21-1 and TPS of 48 cases with breast cancer were detected by enzyme linked immunosorbent assay respectively pre-and post-neoadjuvant chemotherapy.Results:In effective group,CA15-3、CYFRA21-1 and CEA were significantly decreased(P0.05).Through Logistic multiple factor regression analysis,CA15-3?CYFRA21-1and CEA were the better markers of among the five markers to evaluate the neoadjuvant chemotherapy efficacy of breast cancer,and evaluate role from strong to poor by turns.Conclusion:CA15-3 was the best marker of five serum markers to evaluate the neoadjuvant chemotherapy efficacy of breast cancer.
