Quality Control for Chanshukang Granule
- VernacularTitle:产舒康颗粒质量控制研究
- Author:
Lifang CHENG
;
Xiujun CUI
- Publication Type:Journal Article
- Keywords:
ferulic acid;
Chanshukang granule;
TLC;
HPLC;
quality standard
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the quality control method for Chanshukang granule. Methods TLC and HPLC method were used to identify the Chinese herbal medicines. The determination was carried on HPLC, using Kromasil C18 column (200 mm?4.6 mm, 5 ?m), ethanol-2% glacial acetic acid (40∶60) as mobile phase and detected at the wavelength of 324 nm. Results The Chinese herbal medicines, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Placenta Hominis and Radix Glycyrrhizae Preparata, in granules were identified by TLC. The calibration curve was linear in the range of 0.625～3.750 ?g for ferulic acid. The contents in three batches were 0.054%, 0.037%, 0.042% respectively. The average recovery was 96.2% and RSD=2.37%. Conclusion The TLC method can be used for the quality control of four herbal medicines in the granule. The HPLC method is simple, sensitive, accurate and provides a certain evidence for controlling the quality of Chanshukang Granule.
