Methodology for quick finding of leading compounds based on botanical metabonomic concept of determination for mixture by 1H-NMR
- VernacularTitle:基于植物代谢组学混合物氢谱测定概念快速发现先导化合物的方法学研究
- Author:
Jiannong WANG
;
Shiping GU
;
Renxiang TAN
;
Jianwen WANG
- Publication Type:Journal Article
- Keywords:
Carpesium lipskyi Winkl.;
1H-NMR;
metabonomics;
leading compounds
- From:
Chinese Traditional and Herbal Drugs
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To set up a methodology for quick finding of important leading compounds from complex plant samples. Methods A mixture fraction was determined by 1H-NMR techniques to find any evidence, further isolation of the fraction guided with this evidence was carried out. Results Based on the botanical metabonomic concept, a novel valuable sesquiterpene compound has been quickly isolated from the aerial part of Carpesium lipskyi. Conclusion The efficiency for finding of leading compounds could be improved if the isolation is based on metabonomics under the guidence of the new method of botanical mixture determination by 1H-NMR.
