Influence of Different Extraction Technology on Pharmacodynamic Action of Drug Pair of Rhizoma Atractylodis Macrocephalae and Radix Paeoniae Alba
- VernacularTitle:“白术-白芍”药对不同提取工艺对药效作用的影响
- Author:
Changqing CHEN
;
Youliang XIE
;
Zhuoming LI
;
Dongxu JIANG
;
Xiaoping LAI
- Publication Type:Journal Article
- Keywords:
Rhizoma Atractylodis Macrocephalae;
Radix Paeoniae Alba;
Extraction technology;
Gastrointestinal motility adjustment;
Analgesia;
Drug pair
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the influence of different extraction technology on the pharmacodynamic actions of drug pair of Rhizoma Atractylodis Macrocephalae and Radix Paeoniae Alba.Methods The influences of water extraction,alcohol extraction,and SFE-CO2 extraction on pharmacodynamic actions of drug pair of Rhizoma Atractylodis Macrocephalae and Radix Paeoniae Alba were evaluated by mice intestine propulsive motility test,rats repelling acute gastric mucosa damage test,mice twisting test and hot-plate test.Results The paired drugs extracted by SFE-CO2 combining with water extraction or alcohol extraction had better pharmacological actions.Conclusion This study provides a scientific basis for optimizing the extraction technology of drug pair of Rhizoma Atractylodis Macrocephalae and Radix Paeoniae Alba.
