Attenuation of diosgenin on FT-207 in tumor-bearing mice
- VernacularTitle:薯蓣皂苷元对灌胃FT-207荷瘤小鼠的减毒作用
- Author:
Huiying LI
;
Guangzi LI
;
Jingfeng YIN
;
Yanhong BEN
;
Shengwu CHEN
- Publication Type:Journal Article
- Keywords:
diosgenin;
FT-207;
tumor-bearing mice;
attenuation
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To observe the effects of diosgenin on enhancing efficacy and reducing toxicity of FT-207 in tumor-bearing mice. METHODS: The inhibitory rate on tumor growth and immune function of the in tumor-bearing mice model of transplanting MFC,HepA,H_22 and S_180 tumor were measured. RESULTS: Diosgenin had significant restraining effects on MFC in mouse.It could enhance the activity of macrophage and the level of serum hemolysin. CONCLUSION: Diosgenin can enhance the anti-tumor effect of FT-207.It can also improve the immunological function and reduce the adverse reactions of chemotherapy.
