3DP used for controlled-release helicid tablets
- VernacularTitle:三维打印技术制备控释药片工艺研究
- Author:
Dengguang YU
;
Xiangliang YANG
;
Yungan WANG
;
Xiaoyan LI
;
Huibi XU
- Publication Type:Journal Article
- Keywords:
three dimensional printing(3DP);
helicid;
controlled-release tablets;
processes
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the influence of three dimentional printing processes(3DP) on the release of controlled-release helicid tablet. METHODS: Parameters of 3DP,such as skeleton polymer,binder,thickness of powder layering,number of spray painting,subregion ser up and diameter of aperture,were selected in the preparation of donut-shape multilayer controlled-release helicid tablet.Dissolution tests in vitro were carried out to analyse the effect of technological parameters on the release of helicid. RESULTS: Under the condition of fixed subregion and diameter of aperture,the selections of binders and thickness of spray painting were key factors concerning the release period of helicid. CONCLUSION: 3DP processes shows high flexibility and efficacy in the preparation of controlled-release tablets.
