Effect of Niaoduqing Capsule on Kidney Fibrosis Parameters in Chronic Renal Failure
- VernacularTitle:尿毒清胶囊对慢性肾功能衰竭患者肾纤维化指标的影响
- Author:
Qiulin ZHANG
- Publication Type:Journal Article
- Keywords:
KIDNEY FIBROSIS/ TCD therapy;
NIAODUQING CAPSULE/therapeutic use
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the therapeutic effect of Niaoduqing Capsule(NC),which has the actions of lifting clear Qi and purging turbidity,for chronic renal failure(CRF) and to investigate its influence on kidney fibrosis parameters.【Methods】A prospective study was carried out in 78 CRF patients.The patients were equally randomized into two groups.Besides the basic treatment of feeding with small-dose high-quality protein,controlling blood pressure,maintaining water-electrolyte and acid-base balance,Group A received oxyamyli tectus aldehydum and group B received NC.Four weeks constituted one treatment course and the treatment lasted 2 courses.Before and after treatment,the scores of main symptoms and syndrome were counted,and laboratory parameters such as hematoglobin(Hb),red blood cells(RBC) count,serum creatinine(SCr),blood urea nitrogen(BUN),creatinine clearance(CCr),albumin(ALB),total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),serum laminin(LN),precollagen-Ⅲ(PC-Ⅲ) and hyaluronic acid(HA) were assayed.【Results】Total scores of main symptoms and scores of most single symptom were lower,and effect on the symptoms and total therapeutic effect were better in group B than those in group A(P0.05).【Conclusion】NC has an effect on relieving symptoms of CRF,and improving renal function and kidney fibrosis parameters,indicating that NC exerts a better counteraction on kidney fibrosis.
