Effect of Zhenzhumu Pill on Insomnia Induced by Negative Life Events
- VernacularTitle:中药珍珠母丸对负性生活事件所致失眠临床疗效的影响
- Author:
Yunwei CHEN
- Publication Type:Journal Article
- Keywords:
SLEEP DISORDERS/TCM-WM therapy;
ZHENZHUMU PILL/therapeutic use
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】To observe the effect of Zhenzhumu Pill(mainly composed of Concha Margaritifera Usta,Dens Draconis,Lignum Aquilariae Resinatum,Poria cum Radix Pini,Radix Angelicae Sinensis,Radix Rehmanniae Preparata,Radix Codonopsis,Semen Ziziphi Spinosae,Semen Platycladi,etc.) on insomnia induced by negative life events.【Methods】One hundred and twenty-one insomnia patients were randomized into two groups.Groups A(n=63) and B(n=58) received paroxetine hydrochloride Tablets,and group A received decoction of Zhenzhumu Pill additionally.The treatment lasted 90 days.After treatment,sleeping dysfunction rating scale(SDRS) and the Hamilton anxiety scale(HAMA) were used to evaluate the therapeutic effect and adverse reactions.【Results】In group A,22 patients were markedly effective,35 effective,and 6 ineffective.In group B,13 patients were markedly effective,28 effective,and 17 ineffective(P0.05).Meanwhile,the incidence of adverse reactions such as nausea and vertigo was less in group A than that in group B(P