Susceptibility testing and strain identification of Candida species
- VernacularTitle:110株念珠菌的菌种鉴定及药敏试验
- Author:
Xun ZHOU
- Publication Type:Journal Article
- Keywords:
Candida species;
Strain identification;
Susceptibility testing
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the strain and to study the in-vitro susceptibilities of Candida species collected from clinical samples of skin and mucosa to Amphotericin B,Ketoconazole,Miconazole,Itraconazole,Fluconazole,5-Flucytosine and Terbinafin. Methods:110 clinical isolates of yeasts were identified by CHROMAGAR and API20C, meanwhile, the susceptibility to six antifungal drugs was examined by microdilution method using Sensititre Yeast One panels. Results:There were 94 C.albicans, 6 C.tropicalis,4 C.krusei,4 C.glabrata,and 2 C.parapsilosis among 110 isolates of yeasts.There were 0.91%,1.81%,18.28%,1.81%,5.45%,3.63% and 94.55% of isolates displaying resistance to Amphotericin B,Ketoconazole,Miconazole,Itraconazole,Fluconazole,5-Flucytosine and Terbinafin, respectively.Conclusions:C.albicans is the main infection strain in our hospital,and candida species display different resistance to six antifungal drugs. It is necessary to test strain identification and susceptibility of candida species to guild the rational clinical drug use.