Effect of Pingchuanning on the Levels of LTB4 and sICAM-1 of Guinea Pigs with Asthma
- VernacularTitle:平喘宁对哮喘豚鼠白三烯B4、可溶性细胞间粘附分子-1含量的影响
- Author:
Baolin ZHAO
;
Xiangming FANG
- Publication Type:Journal Article
- Keywords:
Pingchuanning;
asthma;
sICAM-1;
LTB4
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Pingchuanning on the levels of LTB4 and sICAM-1 of guinea pigs with asthma. Methods The model guinea pigs of asthma were sensitized with ovalbumin (OVA),the changes of the delitescence of asthma was observed. The levels of LTB4 in serum and sICAM-1 in bronchoalveolar lavage fluid (BALF) were also observed by means of enzyme-linked immunosorbent (ELISA). Result Comparing with the model group,the delitescence of asthma was obviously prolonged in guinea pigs treated by Pingchuanning. The levels of LTB4 and sICAM-1 of guinea pigs with asthma treated by Pingchuanning were significantly lowered (P
