Effect of Yuhonggao on Proliferation and Differentiation of Epidermal Stem Cells in the Process of Rat’s Skin Wound Healing
- VernacularTitle:玉红膏对大鼠创面愈合过程中表皮干细胞增殖分化的影响
- Author:
Fanfei KONG
;
Qingyi HUANG
;
Huanyu KONG
- Publication Type:Journal Article
- Keywords:
Yuhonggao;
wound healing time;
epidermal stem cells;
?1 integrin;
p63
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Yuhonggao on proliferation and differentiation of epidermal stem cells and investigate the mechanism of promoting wound healing. Methods The whole layer skin defection rat was used and randomly divided into 3 groups:Yuhonggao group,Jingwanhong group,model group,with normal rats as control. The condition of skin wound surface and healing time were observed and recorded,and then draw the wound skin. The p63 and?1 integrin expression,the marker of epidermal stem cells,were measured and compared by immunohistochemistry staining. Results Average wound healing time hadn’t significant difference between the Yuhonggao group (13.5? 0.9)d and Jingwanhong group (12.6?0.9)d,which were better than model group (P
