Effects of arecoline on DNA in bone marrow cells
- VernacularTitle:槟榔碱对骨髓细胞内DNA的影响
- Author:
Yubin JI
;
Lianchuang LI
;
Lei YU
- Publication Type:Journal Article
- Keywords:
arecoline;
laser confocal microscope;
Flow Cytometer;
DNA;
RNA;
cell cycle
- From:
Chinese Traditional and Herbal Drugs
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the mechanism of arecoline on damage to DNA through the bone marrow cell experiment in vivo. Methods Laser Confocal Microscope was adopted to measure DNA and RNA of the bone marrow cells marked by AO probe. Influences of arecoline on cell cycle were observed by the Flow Cytometer. Results Injection of arecoline to 20, 10, and 5 mg/kg posologic group, the fluorescence pixel ratio apparently higher than that in blank control group of the bone marrow cell inside RNA/DAN, the difference was significant (P
