Analysis of expression of mitosis checkpoint gene hsMAD2 in colorectal cancer
- VernacularTitle:结肠癌中有丝分裂关卡基因hsMAD2表达的分析
- Author:
Qiong SHI
- Publication Type:Journal Article
- Keywords:
hsMAD2 gene;
Quantitative RT-PCR;
Colorectal cancer
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the expression of mitosis checkpoint gene hsMAD2 in colorectal cancer. Methods:The expression of hsMAD2 gene mRNA in colorectal cancer and normal colorectal tissue of 18 cases was quantitatively detected by RT-PCR. Results:The ratio of hsMAD2 mRNA/ GAPDH mRNA in colorectal cancer and normal colorectal tissue were 0.1235?0.0752 and 0.0312?0.0598,respectively. The results suggested that the expression of hsMAD2 mRNA in colorectal cancer were significant higher than in normal colorectal tissue(P