Expression of survivin,P16~(INK4a) in non-small cell lung carcinoma and their significance
- VernacularTitle:Survivin、P16~(INK4a)在非小细胞肺癌中的表达及意义
- Author:
Xiaoli HAN
- Publication Type:Journal Article
- Keywords:
Survivin;
P16INK4a;
Non-small cell lung carcinoma(NSCLC);
Immunohistochemistry
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the expression of a novel apoptosis inhibitor gene,survivin,in non-small cell lung carcinoma (NSCLC),and its correlation to the expression of P16INK4a gene.Methods:The immunohistochemistry was used to assay the expression of surviving and P16INK4a in tissues of fifty-six cases of non-small cell lung carcinoma,with 12 specimens of benign lesions as the control.Results:Survivin was expressed in 36 out of 56(64.3%)cases of NSCLC,and its expression rate in benign pulmonary diseases was only 8.3%(P
