Effects of Baizhu Huangqi Decoction and Its Effective-part Prescription on Mice Ulcerative Colitis
- VernacularTitle:白术黄芪汤及其有效部位组方对小鼠溃疡性结肠炎的疗效观察
- Author:
Zhongfeng SHI
;
Weiwen CHEN
;
Ruliu LI
;
Qiuxia LI
- Publication Type:Journal Article
- Keywords:
Ulcerative colitis;
Baizhu Huangqi decoction;
Effective parts;
Pharmacology
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of Baizhu Huangqi Decoction and its effective-part prescription on mice ulcerative colitis(UC).Methods The mice UC model was induced by clyster with 2,4,6-trinitrobenzenesulfonic acid(TNBS)and the effects were comprehensively evaluated by disease activity index,the macroscopic and histological assessment of colon mucosa damage and the activity of myeloperoxidase(MPO).Results Both Baizhu Huangqi Decoction and its effective-part prescription had effects on disease activity index(DAI),inflammation index and MPO activity.The effect of effective-part prescription was better than that of UC model group(P
