Effects of Wulong Granules on the Interlerkin mRNA Expression of Nasal Mucosa in Alergic Rhinitis Rats
- VernacularTitle:五龙颗粒对变态反应性鼻炎大鼠鼻黏膜组织白细胞介素mRNA表达的影响
- Author:
Wenyang FU
;
Hiu XIE
;
Dajing XIONG
- Publication Type:Journal Article
- Keywords:
Wulong-granules;
allergic rhinitis;
IL-2 mRNA;
IL-4 mRNA;
IL-6 mRNA
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Wulong granules on the expression of IL-2 mRNA,IL-4 mRNA and IL-6 mRNA in allergic rhinitis(AR) rats in Spleen Qi deficiency type. To establish the clinic treatment principle-tonify Spleen and reinforce Qi of AR through the lab study. Methods Established AR model with combination of disease and Zheng,checked the expression of IL-2 mRNA,IL-4 mRNA and IL-6 mRNA of nasal mucosa were detected with RT-PCR. Results Wulong granules can adjust the expression of mRNA of AR rats' nasal mucosa. It can descend the ascensus of IL-4 mRNA,IL-6 mRNA and the drop of IL-2 mRNA. Conclusion Wulonggranules can show treatment effect to AR rats through adjusting the expression of cell factors such as IL-2 mRNA,IL-4 mRNA and IL-6 mRNA.
