Effect of Solanum nigrum alkaloid on erythrocyte immunity function in tumor-bearing mice
- VernacularTitle:龙葵碱对荷瘤小鼠红细胞免疫功能的影响
- Author:
Yubin JI
;
Meixu WAN
;
Shiyong GAO
;
Xiang ZOU
- Publication Type:Journal Article
- Keywords:
Solanum nigrum alkaloid;
erythrocyte immunity;
membrane fluidity;
tumor-bearing mice
- From:
Chinese Traditional and Herbal Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Solanum nigrum alkaloid on erythrocyte immunity function. MethodsStudying the adherence between erythrocyte immunity and tumor-cell of S180 and H22 tumor-bearing mice; By determining with fluorescence polarization (P) and accounting the micro viscosity (?) with DPH as a probe the erythrocyte membrane fluidity of the S180 and H22 tumor-bearing mice could be investigated. ResultsS. nigrum alkaloid could increase the ratio of adherence anadem between erythrocyte and tumor-cell and promote the erythrocyte membrane fluidity of the two tumor-bearing mice. ConclusionThe inhibition of S. nigrum alkaloid on tumor can be accomplished through improving the erythrocyte membrane fluidity of two tumor-bearing mice and renewing erythrocyte immunity of tumor-bearing mice.
