Whole Body Simulation and Visualization of Metabolic Process of ~(18)F 2-fluoro-2-deoxy-D-glucose
- VernacularTitle:~(18)F氟代脱氧葡萄糖代谢过程的全身模拟与可视化
- Author:
Yunfeng CUI
;
Jing BAI
;
Yingmao CHEN
;
Jiahe TIAN
- Publication Type:Journal Article
- Keywords:
simulation;
visualization;
metabolism;
compartment model;
2-fluoro-2-deoxy-D-glucose(FDG);
positron emission tomography(PET)
- From:Space Medicine & Medical Engineering
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To simulate the metabolic distribution process of 18F 2-fluoro-2-deoxy-D-glucose(FDG) in human body and to visualize this distribution process through 3D images with high resolution and high quality. Methods The model parameters of FDG metabolism in tissues were estimated through clinical experiments, and the curves which represent the FDG metabolic process in tissues were calculated using the model parameters and blood input function. This FDG distribution process in human body was visualized basing on the high-resolution anatomical structure. Results The simulation and visualization results directly and clearly displayed the FDG metabolic distribution process after injection to human body. The properties of the FDG distribution process represented by our simulation were consistent with that represented by clinical experiment. Conclusion The method presented in this study is effective to simulate and visualize human functional information of metabolism, and it may provide a useful tool for education and research on nuclear imaging.
