Influence of Buyanghuanwu Decoction on Cerebral Infarct Volume and Pathological Changes after Cerebral Ischemia and Reperfusion
- VernacularTitle:补阳还五汤对脑缺血再灌注后脑梗死体积及病理学改变的影响
- Author:
Yanling ZHAO
;
Youzhi QU
- Publication Type:Journal Article
- Keywords:
Buyanghuanwu Decoction;
cerebral ischemia;
pathology;
cerebral infarct volume
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of Buyanghuanwu (BYHW) Decoction on cerebral infarct volume and pathological changes after cerebral ischemia and reperfusion. Methods The model of focal cerebral ischemia and reperfusion was made by thread embolism method. Healthy male SD rats were divided randomly into sham-operated group, model group and BYHW Decoction group. Infarct volume was detected by triphenyltetrazolium chloride (TTC) staining and pathological changes were observed microscopically in HE stained sections. Results In BYHW Decoction group, infarct volume was significantly smaller than that in model group (P