IMMUNOHISTOCHEMICAL QUANTITY ANALYSIS OF DENDRITIC CELLS AND T LYMPHOCYTES IN HUMAN CERVICAL INTRAEPITHELIAL NEOPLASIA AND INVASIVE CARCINOMA
- VernacularTitle:人宫颈上皮内瘤变和浸润癌组织中树突状细胞及T细胞的免疫组织化学定量分析
- Author:
Xinying CHANG
;
Junmin TANG
- Publication Type:Journal Article
- Keywords:
Cervical intraepithelial neoplasia;
Cervical carcinoma;
Dendritic cell;
T lymphocyte;
Immunohistochemical quantity analysis;
Human
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the number,distribution and expression intensity of dendritic cells and T lymphocytes in human cervical intraepithelial neoplasia and invasive carcinoma for seeking biotherapeutic evidence of cervical carcinoma. Methods The number,distribution and expression intensity of CD-(1a),S-100,CD-3, CD-8 positive cells were determined in cervical intraepithelial neoplasia and invasive carcinoma and human normal cervix tissue as the control,by using immunohistochemical technique and computerized imaging analysis system. Results Compared with human normal cervical tissue,the number and the expression intensity of CD~+-(1a),S-100~+,CD~+-3,CD~+-8 cells in cervical intraepithelial neoplasia significantly increased(P
