Value of ~(99)Tc~m-MIBI double-phase imaging on anatomical diagnosis of primary hyperparathyroidism
- VernacularTitle:~(99)Tc~m-MIBI双时相显像定位诊断原发性甲状旁腺机能亢进症的价值
- Author:
Dong DUAN
- Publication Type:Journal Article
- Keywords:
Primary hyperparathyroidism;
Parathyroid;
Radionuclides imaging;
MIBI
- From:
Journal of Chongqing Medical University
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical value of 99Tcm-MIBI double-phase imaging on anatomical diagnosis of primary hyperparathyroidism(PHPT).Methods:Double phase 99Tcm-MIBI imaging was performed in 15 normal controls and 51 patients with primary hyperparathyroidism proven by physical examination and biochemical blood tests(for the latter group,the examination was performed in 1 week before the operation).Tomographic scanner was arranged for part of the patients.The uptake ratio was calculated and compared by ROI sequence.Results:Comparing the imaging results with those of histopathology,the sensitivity percentages of early and delayed phases to parathyroid adenomas were 78.3%(36/46)and 91.3%(42/46),and those to parathyroid hyperplasia were 23.8%(5/21)and 47.6%(10/21)respectively.Six lesions of parathyroid were demonstrated by SPECT tomographic imaging.The positive rate of lesions(weighting between 500 to 1500 mg)was 82.4%,and all lesions over 1500 mg appeared to be positive,those less than 500mg appeared to be negative in 99Tcm-MIBI double-phase imaging.For positive parathyroid adenoma group,the uptake ratio of delayed phase was significant higher than that of early phase(P
