Effect of inhalable particulate matter from roadside dust on airway inflammation in rats
- VernacularTitle:扬尘可吸入颗粒物对大鼠支气管肺组织致炎作用的研究
- Author:
Yu WU
- Publication Type:Journal Article
- Keywords:
Dust;
Inhalable particulate matter;
Airway inflammation
- From:
Journal of Chongqing Medical University
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effect of roadside dust inhalable particulate matter on airway inflammation in rats.Methods:Particles at roadside were collected,analyzed and PM10-treat model of rats were established.Lung tissue histopathology was observed.The counts of total leukocytes and neutrophils in bronchoalveolar lavage fluid(BALF)and superoxide dismutase(SOD),glutathion peroxidase(GSH-Px),malondiadehyde(MDA),cytokin-induced neutrophil chemotactics(CINC)in lung homogenate were measured.Results:The counts of total leukocytes,macrophages and neutrophils in PM10-treat group were increased significantly than those in control group(P
