Protective Effect of Gualou Gancao Granules on Pneumonia Mice Infected Influenza Virus
- VernacularTitle:瓜蒌甘草颗粒对流感病毒肺炎小鼠保护作用研究
- Author:
Guanghua TANG
;
Rujin YU
;
Liangduo JIANG
- Publication Type:Journal Article
- Keywords:
Viral pneumonia;
Influenza virus;
Gualou Gancao Granules;
Pharmacodynamics
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Gualou Gancao Granules(GLGC)on influenza virus pneumonia mice.Methods The mice model of viral pneumonia was established by nose inhalation of influenza virus FM1.The treatment groups were administered GLGC with ribavirin served as control drug.The mortality,body weight,lung index,viral blood agglutination titer of influenza virus pneumonia mice were observed.Results Compared with the model group,GLGC can reduce the mortality of influenza virus pneumonia mice,prolong the average living days,inhibit the body weight decrease,and depress the lung index and viral titer distinguishingly.Conclusion GLGC,which derived from the therapeutic principle of clearing away heat-evil and eliminating sputum,has an affirmative effect on influenza virus pneumonia mice.
