Antioxidation and Immuno-regulation Effects of Jiawei Zhisou Powder on Hypersensitive Asthma Mice
- VernacularTitle:加味止嗽散对过敏性哮喘小鼠抗氧化和免疫调节的作用
- Author:
Naiyu XU
;
Zhenlun GU
;
Meilin XIE
- Publication Type:Journal Article
- Keywords:
Effective fraction of Jiawei Zhisou Powder;
Asthma;
Antioxidant;
Immuno-regulation
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the antioxidation and immuno-regulation effects of the active fraction in Jiawei Zhisou Powder.Methods Hypersensitive asthma mice were established by the miscible liquids of ovalbumin(OA)and Al(OH)3.The influences of the powder on the contents of SOD and MDA in the serum and lung tissue of mice were observed and the contents of IL-4 and IFN-?in supernatant of mouse spleen cells cultured in vitro were measured by enzyme-linked immunosorbent assay.And Jiawei Zhisou Powder and dexamethasone were administered to normal mice respectively,then the immune organs weight were measured and the spleen and thymus indexes of mice were calculated.Results Compared with the normal group,the contents of SOD and IFN-?were significantly decreased,while MDA and IL-4 contents were obviously enhanced in asthma group(P
