Content Determination of Aconitine-type Alkaloids in Bitongxiao Ointment by Acid-dye Colorimetry
- VernacularTitle:酸性染料比色法测定痹痛消膏中乌头生物碱的含量
- Author:
Dake CAI
;
Geng LI
;
Shaozhong PENG
;
Yaohui HE
;
Zhongze LIN
;
Tingwei GU
;
Ziren SU
- Publication Type:Journal Article
- Keywords:
Spectrophotometry of ion-couple extraction;
Aconitine-type alkaloids;
Content determination
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the content of aconitine-type alkaloids in Bitongxiao Ointment,and to control the limits of aconitine-type alkaloids in the ointment.Methods Acid-dye colorimetry was employed and methodology was examined for linear range,average recovery,precision,exclusivity and stability.Results The method has a good precision and stability.The linear range of aconitine-type alkaloids was in 0.111 9～0.714 mg(r=0.999 3),and the average recovery was 97.4 %.Conclusion The method is accurate,reliable,simple,can be used to determine the content of aconitine-type alkaloids in Bitongxiao Ointment.
