Epidemiological Characteristics of Anaphylactic Shock Caused by Qingkailing Injection
- VernacularTitle:清开灵注射剂致过敏性休克流行病学特点研究
- Author:
Jiarui WU
;
Bing ZHANG
- Publication Type:Journal Article
- Keywords:
Qingkailing Injection;
Anaphylactic shock;
Epidemiology
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the causations and rules of anaphylactic shock caused by Qingkailing Injection.Method The analysis was conducted on 66 cases of anaphylactic shock caused by Qingkailing Iinjection collected from medical journals in 1978～2005 by epidemiology and bibliometrics methods.Results There were a large number(40.91 %)of young sufferers from age 18 to 44 in the cases reported.The male cases was 29(44.62 %)and the female cases was 36(55.38 %)in the 65 cases with gender recordation.In primary disease,the upper respiratory tract infection rate was up to the highest 75.76 %.The dosage of Qingkailing Injection was in the range of 20～40 mL,the occurrence of anaphylactic shock was commonly within 30 mins after injection,and 68 %was within 10 min.The anaphylactic shock patients were cured after emergency treatment except 5 were died.Conclusion Qingkailing Injection can induce dangerous even fatal anaphylactic shock,its mechanism may be related to the constitution of the patient,ingredient of the drug self and diagnosis warp.Treatment based on syndrome differentiation combined with traditional Chinese medicine theory,dosage control,unnecessary compatibility decrease,prevention consciousness should be pay more attention in the clinical application.
