Effect of Pingchuanling on eosinophils count and its apoptosis in bronchus asthma rats
- VernacularTitle:平喘灵对哮喘大鼠嗜酸性粒细胞计数及凋亡的影响
- Author:
Jintian LI
;
Juan LI
;
Yongqi LIU
;
Junming CHEN
;
Xiaoli CHENG
;
Huiyuan CHU
;
Chunlu YAN
- Publication Type:Journal Article
- Keywords:
Pingchuanling(PCL);
bronchus asthma;
Fas;
Bcl-2;
rat
- From:
Chinese Traditional Patent Medicine
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the therapeutic effects and the related mechanism of Pingchuanling(PCL) on bronchial asthma in rats. METHODS: The rats asthma model was established by ovalbumin(OVA) sensitization.The SD rats were divided into the normal control group,asthma model group,dexamethasone group,low and higher dose of PCL group.Eos in serum and BALF were taken count of and tissue slice dyed with HE were observed.In addition Fas,Bcl-2 expression in lung tissue were examined by immunotisssuchemical technology. RESULTS: Eos count in serum and BALF of asthma model group were increased significantly as compared with that in normal animals.Asthma induced delitescence also were shorten obviously,the differences between the groups were all significant(P
