Effects of Tongxieercaofang on IL-2 Level in Serum and NO, NOS in Intestinal Mucosa of Rats with Ulcerative Colitis
- VernacularTitle:痛泻二草方对溃疡性结肠炎模型大鼠血清IL-2含量及肠黏膜NO含量、NOS活性的影响
- Author:
Yongqiang DUAN
;
Changhe CHENG
;
Yingxia CHENG
- Publication Type:Journal Article
- Keywords:
Tongxieercaofang;
ulcerative colitis;
IL-2;
NO;
NOS
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study effects of Tongxieercaofang (TXECF) on levels of IL-2 in serum and NO, NOS in intestinal mucosa tissue of rats with ulcerative colitis, and further to research the mechanism of' restoreing ulcer of TXECF. Methods Ulcerative colitis model was established by immunization and stimulus method partly. 50 rats were divided into 5 groups randomly:normal group, model group, TXECF group, Tongxieyaofang (TXYF) group, Bupiyichangwan (BPYCW) group. Then the effect of TXECF on levels of IL-2 in serum and NO, NOS in intestinal mucosa tissue were observed. Results In successful model group, IL-2 in serum was much lower than that of normal group (P