Effect of Acupuncture on Neurofunction,Hemorheology and Inflammatory Factors in Radiculitis Rats
- VernacularTitle:针刺对神经根炎模型大鼠神经功能、血液流变学和炎症因子的影响
- Author:
Ziqi ZHUANG
;
Dunjian WANG
;
Fanggen TANG
;
Lingyun WU
;
Xiaobing LI
- Publication Type:Journal Article
- Keywords:
RADICULOPATHY /acup-moxibustion therapy;
POINT EX-B2(JIAJI);
POINT BL40(WEIZHONG);
POINTS,XI(CLEFT);
DISEASE MODELS,ANIMAL;
RATS
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】To observe the effect of acupuncture mainly on cleft points on chemical radiculitis rats and to explore the therapeutic mechanism of acupuncture on lumbar disc prolapse.【Methods】Twenty-four rats with chemical radiculitis were equally randomized into acupuncture group and model group,and another 12 normal rats were in the blank control group.Acupuncture group received acupuncture on acupoints of Jiaji(EX-B2)and Weizhong(BL40)and cleft points of Foot-Shaoyang Meridian and Foot-Taiyang Meridian for 28 days.After treatment,rat behavioral changes and morphological features of nerve cells were observed,the weight of inflammation filter paper was detected,and hemorheologic parameters,nitric oxide (NO) and interleukin 6(IL-6) were assayed.【Results】Acupuncture improved the motor function of affected limb,recovered the senses of pain and tough,improved hemorheologic parameters,reduced the inflammatory reaction,relieved degeneration of nerve root,and decreased the contents of inflammatory factors(P