Clinical study on the treatment of acute bacterial infection by domestic ceftizoxime sodium
- VernacularTitle:国产头孢唑肟钠治疗中重度细菌性感染的临床观察
- Author:
Chuan LIU
- Publication Type:Journal Article
- Keywords:
Ceftizoxime;
Bacterial infection;
Safety;
Efficacy
- From:
Journal of Chongqing Medical University
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy and safety of domestic ceftizoxime sodium on the treatment of acute bacterial infection compared with the imported one.Methods:A randomized,comparative,double blinded trial was conducted.The usage of the two medicines was the same: The dose was 2.0g,bid and the duration of treatment was 7~14 days.The clinical efficacy,bacterial eradication and adverse reaction were observed.Results:The total number of final evaluated subjects was 50 with 25 subjects in domestic ceftizoxime sodium group and 25 subjects in imported ceftizoxime sodium group(control group).Clinical efficacy rate and bacterial eradication rate for domestic ceftizoxime sodium were 96.00% and 89.47%,respectively.Clinical efficacy rate and bacterial eradication rate for imported ceftizoxime sodium were 100% and 100%.No adverse reaction was observed in two groups.Conclusion:Domestic ceftizoxime sodium has the same efficacy and safety as the imported one on the treatment of acute bacterial infection.