Effect of Duzhonghongjingtian Capsule on Experimental Cerebral Ischemia in Rats
- VernacularTitle:杜仲红景天胶囊对大鼠脑缺血的保护作用
- Author:
Yunhua CHEN
;
Shuofeng ZHANG
;
Jianning SUN
- Publication Type:Journal Article
- Keywords:
Duzhong Hongjingtian capsule;
cerebral ischemia;
middle cerebral artery occlusion;
capillary vessel permeability;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective effect of Duzhong Hongjingtian Capsule (DHC) on cerebral ischemia in rats. Methods Thrombotic ischemia and middle cerebral artery occlusion (MCAO) induced by FeCl3 in rats was used to observe the protective effect of DHC on ischemia stroke, and common carotid artery occlusion (CCAO) rats was used to analyze the effect of DHC on blood brain barrier (BBB) permeability. Results DHC could improve the abnormal behavior of MCAO rats and decrease the infarction area and water content in the brain of MCAO rats. DHC could also improve the cerebral blood flow on MCAO rats and significantly reduce the permeability for evans' blue (EB) of CCAO rats. Conclusions DHC can protect the brain ischemic injury.
