Determination of Ephedrine in Lianma Spraying by HPLC
- VernacularTitle:高效液相色谱法测定链麻喷雾剂中麻黄碱的含量
- Author:
Wei ZHAO
;
Xuefeng HUANG
;
Songfeng PENG
- Publication Type:Journal Article
- Keywords:
Lianma Spraying;
ephedrine;
HPLC
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for determination of ephedrin in Lianma Spraying by HPLC. Method The analysis was carried out on C18 column (4.6 mm?200 mm, 5 ?m) by HPLC, the mobile phase was NaH2PO3-CH3OH-CH3CN-C3H15N (600∶320∶80∶1), the flow rate was 1.0 mL/min, the column temperature was 30 ℃, and detective wavelength was 207 nm. Result The linear range of ephedrin was 0.031 2~0.187 2 mg/mL, the average recovery rate was 98.94%, RSD was 0.8%. Conclusion The method is simple, rapid, accurate and reliable, and can be used to control the quality of the products.
